Stock Scorecard
Stock Summary for Ionis Pharmaceuticals Inc (IONS) - $83.69 as of 11/28/2025 3:47:53 PM EST
Total Score
5 out of 30
Safety Score
48 out of 100
Currently on the following lists
None
Tim's Recommendation
Avoid
Growth List Algorithm Criteria for IONS
| Positive Quarterly and Annual earnings growth | |
| P/E ratio less than Industry P/E Ratio | |
| P/E ratio less than Sector P/E Ratio | |
| P/E ratio that is half the Annual earnings growth rate (or less) | |
| Positive net cash position the past year and most recent quarter | |
| Equity to debt ratio greater than 0.75 for past year and most recent quarter | |
| Positive net income past year and 12 trailing months | |
| Free cash flow ratio greater than 0 and less than 10 |
Small Cap List Algorithm Criteria for IONS
| Revenue growing by at least 20% average per year over the last 5 years | |
| Market Capitalization under 2 billion | |
| Price to Sales (P/S) ratio 12 trailing months less than Industry P/S ratio twelve trailing months | |
| Price to Sales (P/S) ratio 12 trailing months less than Sector P/S ratio twelve trailing months | |
| Net Income past year > Net Income prior year OR Net Income 12 trailing months > Net Income prior year OR Net Income 12 trailing months > Net Income past year |
Dividend List Algorithm Criteria for IONS
| Declared an ex-dividend date | |
| Forward annual dividend rate greater than 2 | |
| Positive net cash position the past year and most recent quarter | |
| Equity to debt ratio greater than 0.75 for past year and most recent quarter | |
| Current ratio most recent quarter greater than 2 | |
| Cash Flow per Share greater than Trailing Dividend Rate |
Bonus Criteria for IONS
| P/E ratio less than five-year Average P/E ratio | |
| Last Price to 52 Week Low Ratio Less Than 1 | |
| Total Cash Per Share > Last Day Price | |
| P/S Ratio < 1 | |
| P/B Ratio < 1 |
Safety Rating Criteria for IONS (48 out of 100)
| Stock Price Rating (Max of 10) | 9 |
| Historical Stock Price Rating (Max of 10) | 8 |
| Stock Price Trend (Max of 10) | 10 |
| Book Value (Max of 10) | 3 |
| Book Value to Price (Max of 10) | 0 |
| Analyst Buy Ratings (Max of 5) | 5 |
| Analyst Strong Buy Ratings (Max of 5) | 5 |
| Dividend Yield Percentage (Max of 10) | 0 |
| Operating Margin (Max of 10) | 0 |
| Trading Volume (Max of 10) | 8 |
| Price to Earnings (Max of 10) | 0 |
| Geopolitical Risk Adjustment (Always 0 for USA or a Negative Number for Non-USA) | 0 |
Latest News for for IONS
Financial Details for IONS
Company Overview |
|
|---|---|
| Ticker | IONS |
| Company Name | Ionis Pharmaceuticals Inc |
| Country | USA |
| Description | Ionis Pharmaceuticals, Inc. is a leading biopharmaceutical innovator based in Carlsbad, California, recognized for its advanced RNA-targeted therapies that tackle severe and complex health challenges. The company leverages its proprietary antisense technology to target critical unmet medical needs across therapeutic areas, including neurological disorders, cardiovascular diseases, and oncology. Supported by a robust pipeline of proprietary and partnered assets, Ionis is well-positioned within the precision medicine sector, driving significant advancements that enhance patient outcomes. With a strong focus on research and development, Ionis not only solidifies its role as an industry leader but also underscores its potential for continued growth and impact in the biopharmaceutical landscape. |
| Sector Name | HEALTHCARE |
| Industry Name | BIOTECHNOLOGY |
| Most Recent Quarter | 9/30/2025 |
| Next Earnings Date | N/A |
Stock Price History |
|
| Last Day Price | 83.69 |
| Price 4 Years Ago | 30.43 |
| Last Day Price Updated | 11/28/2025 3:47:53 PM EST |
| Last Day Volume | 852,941 |
| Average Daily Volume | 2,811,078 |
| 52-Week High | 82.95 |
| 52-Week Low | 23.95 |
| Last Price to 52 Week Low | 249.44% |
Valuation Measures |
|
| Trailing PE | N/A |
| Industry PE | 43.72 |
| Sector PE | 89.93 |
| 5-Year Average PE | -40.70 |
| Free Cash Flow Ratio | 40.04 |
| Industry Free Cash Flow Ratio | 14.11 |
| Sector Free Cash Flow Ratio | 29.09 |
| Current Ratio Most Recent Quarter | 2.79 |
| Total Cash Per Share | 2.09 |
| Book Value Per Share Most Recent Quarter | 3.84 |
| Price to Book Ratio | 21.68 |
| Industry Price to Book Ratio | 33.64 |
| Sector Price to Book Ratio | 33.13 |
| Price to Sales Ratio Twelve Trailing Months | 13.85 |
| Industry Price to Sales Ratio Twelve Trailing Months | 32.13 |
| Sector Price to Sales Ratio Twelve Trailing Months | 16.04 |
| Analyst Buy Ratings | 10 |
| Analyst Strong Buy Ratings | 8 |
Share Statistics |
|
| Total Shares Outstanding | 161,974,000 |
| Market Capitalization | 13,555,604,060 |
| Institutional Ownership | 106.50% |
Dividends |
|
| Ex-Dividend Date | N/A |
| Previous Dividend Amount | 0.0000 |
| Current Dividend Amount | 0.0000 |
| Total Years Dividend Increasing | N/A |
| Trailing Annual Dividend Rate | 0.00 |
| Trailing Annual Dividend Yield | 3.07% |
| Forward Annual Dividend Rate | 0.00 |
| Forward Annual Dividend Yield | 0.00% |
| 5-Year Dividend Payments Count | 0 |
| 3-Year Average Dividend Yield | 0.00% |
| 5-Year Average Dividend Yield | 0.00% |
| 1-Year Dividend Growth Rate Percentage | 0.00% |
| 3-Year Dividend Growth Rate Percentage | 0.00% |
| 5-Year Dividend Growth Rate Percentage | 0.00% |
| All-Time Dividend Growth Rate Percentage | 0.00% |
| Dividend Payout Ratio | N/A |
Income Statement |
|
| Quarterly Earnings Growth YOY | -43.70% |
| Annual Earnings Growth | -23.92% |
| Reported EPS 12 Trailing Months | -1.61 |
| Reported EPS Past Year | -0.84 |
| Reported EPS Prior Year | -2.81 |
| Net Income Twelve Trailing Months | -256,342,000 |
| Net Income Past Year | -453,897,000 |
| Net Income Prior Year | -366,286,000 |
| Quarterly Revenue Growth YOY | 17.10% |
| 5-Year Revenue Growth | -8.89% |
| Operating Margin Twelve Trailing Months | -102.20% |
Balance Sheet |
|
| Total Cash Most Recent Quarter | 338,341,000 |
| Total Cash Past Year | 242,077,000 |
| Total Cash Prior Year | 399,266,000 |
| Net Cash Position Most Recent Quarter | -257,567,000 |
| Net Cash Position Past Year | -1,003,408,000 |
| Long Term Debt Past Year | 1,245,485,000 |
| Long Term Debt Prior Year | 1,229,501,000 |
| Total Debt Most Recent Quarter | 595,908,000 |
| Equity to Debt Ratio Past Year | 0.32 |
| Equity to Debt Ratio Most Recent Quarter | 0.51 |
| Total Stockholder Equity Past Year | 588,351,000 |
| Total Stockholder Equity Prior Year | 386,686,000 |
| Total Stockholder Equity Most Recent Quarter | 617,967,000 |
Free Cash Flow |
|
| Free Cash Flow Twelve Trailing Months | -302,662,000 |
| Free Cash Flow Per Share Twelve Trailing Months | -1.87 |
| Free Cash Flow Past Year | -546,227,000 |
| Free Cash Flow Prior Year | -335,524,000 |
Options |
|
| Put/Call Ratio | 0.04 |
| Has Options | Options Chain |
| Liquidity Rating | |
Technical Analysis |
|
| Yahoo Finance Chart | Yahoo Finance Chart |
| MACD | 2.05 |
| MACD Signal | 1.43 |
| 20-Day Bollinger Lower Band | 32.39 |
| 20-Day Bollinger Middle Band | 60.43 |
| 20-Day Bollinger Upper Band | 88.47 |
| Beta | 0.31 |
| RSI | 69.93 |
| 50-Day SMA | 43.57 |
| 150-Day SMA | 42.82 |
| 200-Day SMA | 41.91 |
System |
|
| Modified | 11/29/2025 1:15:18 AM EST |